KLF6

Across TCGA cell cohorts, KLF6 mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. PANCREAS shows the largest number of these associations.

The most reproducible KLF6-associated genes across cancer lineages are TECTB, SERPINA12, and ADH1B. Each is linked with KLF6 in more than 1 cancer types. Because this analysis shows association rather than direction, both KLF6-to-partner and partner-to-KLF6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TECTB grouped by KLF6-low versus KLF6-high in PANCREAS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KLF6→partner) and Y-score (partner→KLF6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	TECTB →	+0.942	+4.011	<.001	.009	3	1
PANCREAS	SERPINA12 →	+0.012	+4.614	<.001	.004	3	1
PANCREAS	ADH1B →	+0.782	+4.491	<.001	.003	3	1
BLOOD_Lymphoma	C1orf87 →	+0.021	+4.867	.008	.009	3	1
BLOOD_Lymphoma	ART5 →	+0.122	+4.867	<.001	.009	3	1
BLOOD_Lymphoma	DYNAP →	+0.102	+4.867	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

TECTB by KLF6 expression — PANCREAS

Explore this box plot interactively →