KLF3

Across TCGA patient cohorts, KLF3 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,756 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible KLF3-associated proteins across cancer lineages are RASSF4, KLF3_S111, and KLF3_S92. Each is linked with KLF3 in more than 6 cancer types. Because this analysis shows association rather than direction, both KLF3-to-partner and partner-to-KLF3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KLF3 versus RASSF4 in LSCC, with a Pearson correlation of -0.43.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (KLF3→partner) and Y-score (partner→KLF3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	RASSF4 →	-0.474	-0.590	<.001	<.001	3	7
PDAC	KLF3_S111 →	+0.840	+0.393	<.001	<.001	3	5
LSCC	KLF3_S92 →	+0.715	+0.528	<.001	<.001	3	4
LSCC	S100PBP_S73 →	-0.579	-0.613	.001	<.001	3	4
PDAC	CORO2A →	+0.600	+0.515	<.001	<.001	3	4
UCEC	CTNNB1 →	+0.402	+0.610	.002	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,756 associations by consensus.

KLF3 vs RASSF4 — LSCC

Explore this scatter interactively →