KLF2P1

Across TCGA patient cohorts, KLF2P1 mutation is significantly associated with the RNA expression of many other genes, with 23 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KLF2P1-associated genes across cancer lineages are RNU6-281P, OTOP1, and OFD1P11Y. Each is linked with KLF2P1 in more than 1 cancer types. Because this analysis shows association rather than direction, both KLF2P1-to-partner and partner-to-KLF2P1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-281P grouped by KLF2P1-low versus KLF2P1-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KLF2P1→partner) and Y-score (partner→KLF2P1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RNU6-281P →	+0.373	+7.816	<.001	.008	3	1
UCEC	OTOP1 →	+0.686	+3.622	<.001	.004	3	1
SKCM	OFD1P11Y →	+0.039	+7.816	<.001	.008	3	1
UCEC	OR6C72P →	+0.093	+4.290	<.001	.001	3	1
UCEC	RNU6-441P →	+0.249	+4.885	<.001	.002	3	1
UCEC	MIR601 →	+0.602	+3.091	.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 23 associations by consensus.

RNU6-281P by KLF2P1 expression — SKCM

Explore this box plot interactively →