KLF2

Across TCGA patient cohorts, KLF2 protein abundance is significantly associated with the RNA expression of many other genes, with 1,128 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible KLF2-associated genes across cancer lineages are RAB38, RNU4-62P, and ZMYND8. Each is linked with KLF2 in more than 1 cancer types. Because this analysis shows association rather than direction, both KLF2-to-partner and partner-to-KLF2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KLF2 versus RAB38 in BRCA, with a Pearson correlation of -0.43.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KLF2→partner) and Y-score (partner→KLF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RAB38 →	-1.598	-0.724	.008	.004	3	2
BRCA	RNU4-62P →	+2.198	+0.727	.003	.003	3	2
LUAD	ZMYND8 →	+0.820	+0.636	.009	.004	3	1
LUAD	CENPT →	+0.469	+0.712	.004	.002	3	1
LUAD	SEMA3G →	+0.868	+0.649	<.001	<.001	3	1
LUAD	NOVA2 →	+0.390	+0.751	.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,128 associations by consensus.

KLF2 vs RAB38 — BRCA

Explore this scatter interactively →