KLF16

Across TCGA patient cohorts, KLF16 protein abundance is significantly associated with the RNA expression of many other genes, with 5,563 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible KLF16-associated genes across cancer lineages are H2AC14, GINS2, and CPAMD8. Each is linked with KLF16 in more than 3 cancer types. Because this analysis shows association rather than direction, both KLF16-to-partner and partner-to-KLF16 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KLF16 versus H2AC14 in HNSC, with a Pearson correlation of 0.29.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KLF16→partner) and Y-score (partner→KLF16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	H2AC14 →	+2.022	+0.457	<.001	.001	3	4
HNSC	GINS2 →	+0.951	+0.464	.001	.007	3	3
LUAD	CPAMD8 →	-0.752	-0.293	.002	<.001	3	3
LSCC	CEP152 →	+0.859	+0.379	<.001	<.001	3	3
LSCC	CENPF →	+1.154	+0.376	<.001	<.001	3	3
GBM	ATP8A1 →	-0.822	-0.431	.002	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,563 associations by consensus.

KLF16 vs H2AC14 — HNSC

Explore this scatter interactively →