KLF16

Across TCGA patient cohorts, KLF16 mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KLF16-associated genes across cancer lineages are CLP, Mesangial cells, and Sebocytes. Each is linked with KLF16 in more than 1 cancer types. Because this analysis shows association rather than direction, both KLF16-to-partner and partner-to-KLF16 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CLP grouped by KLF16-low versus KLF16-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KLF16→partner) and Y-score (partner→KLF16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CLP →	-0.074	-3.127	.031	.020	3	1
UCEC	Mesangial cells →	-0.053	-3.159	.011	.020	2	1
UCEC	Sebocytes →	-0.033	-3.148	.015	.020	1	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

CLP by KLF16 expression — UCEC

Explore this box plot interactively →