KLF15

Across TCGA patient cohorts, KLF15 protein abundance is significantly associated with the RNA expression of many other genes, with 822 significant associations in total. GBM shows the largest number of these associations.

The most reproducible KLF15-associated genes across cancer lineages are SPRTN, ISM1, and CSTF2. Each is linked with KLF15 in more than 1 cancer types. Because this analysis shows association rather than direction, both KLF15-to-partner and partner-to-KLF15 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KLF15 versus SPRTN in GBM, with a Pearson correlation of 0.55.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KLF15→partner) and Y-score (partner→KLF15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SPRTN →	+0.324	+1.323	.006	.009	3	1
GBM	ISM1 →	+0.844	+1.269	.005	.002	3	1
GBM	CSTF2 →	+0.490	+1.551	.001	.005	3	1
GBM	CD40LG →	+0.634	+1.839	<.001	.001	3	1
GBM	ZDHHC15 →	+0.838	+1.151	.002	.003	3	1
GBM	ESRP2 →	+0.596	+1.136	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 822 associations by consensus.

KLF15 vs SPRTN — GBM

Explore this scatter interactively →