KLF15

Across TCGA cell cohorts, KLF15 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,104 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible KLF15-associated GO terms across cancer lineages are RNA catabolic process, Regulation of peptidyl-lysine acetylation, and Regulation of muscle system process. Each is linked with KLF15 in more than 13 cancer types. Because this analysis shows association rather than direction, both KLF15-to-partner and partner-to-KLF15 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA catabolic process grouped by KLF15-low versus KLF15-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KLF15→partner) and Y-score (partner→KLF15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	RNA catabolic process →	+0.081	+1.638	<.001	<.001	3	14
OVARY	Regulation of peptidyl-lysine acetylation →	-0.165	-0.688	.009	<.001	3	14
LUNG_NSCLC_LUSC	Regulation of muscle system process →	-0.078	-0.761	.002	.006	3	13
BONE	Regulation of monoatomic cation transmembrane transport →	-0.071	-1.390	<.001	<.001	3	11
BONE	Nucleic acid catabolic process →	+0.066	+1.512	<.001	<.001	3	11
SKIN	Aminoacyl-tRNA metabolism involved in translational fidelity →	+0.117	+1.356	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,104 associations by consensus.

RNA catabolic process by KLF15 expression — BONE

Explore this box plot interactively →