KLF14

Across TCGA patient cohorts, KLF14 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,050 significant associations in total. STAD shows the largest number of these associations.

The most reproducible KLF14-associated GO terms across cancer lineages are Positive regulation of epithelial to mesenchymal transition, Non-canonical Wnt signaling pathway, and Cellular response to vascular endothelial growth factor stimulus. Each is linked with KLF14 in more than 15 cancer types. Because this analysis shows association rather than direction, both KLF14-to-partner and partner-to-KLF14 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of epithelial to mesenchymal transition grouped by KLF14-low versus KLF14-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KLF14→partner) and Y-score (partner→KLF14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Positive regulation of epithelial to mesenchymal transition →	+0.057	+0.199	<.001	<.001	3	16
STAD	Non-canonical Wnt signaling pathway →	+0.057	+0.268	<.001	<.001	3	15
STAD	Cellular response to vascular endothelial growth factor stimulus →	+0.056	+0.214	<.001	<.001	3	15
STAD	Membrane biogenesis →	+0.053	+0.271	<.001	<.001	3	15
STAD	Regulation of animal organ morphogenesis →	+0.047	+0.284	<.001	<.001	3	15
STAD	Positive regulation of stress fiber assembly →	+0.057	+0.188	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,050 associations by consensus.

Positive regulation of epithelial to mesenchymal transition by KLF14 expression — STAD

Explore this box plot interactively →