KLF14

Across TCGA cell cohorts, KLF14 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible KLF14-associated genes across cancer lineages are MYOD1 and FCN2. Each is linked with KLF14 in more than 1 cancer types. Because this analysis shows association rather than direction, both KLF14-to-partner and partner-to-KLF14 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MYOD1 grouped by KLF14-low versus KLF14-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KLF14→partner) and Y-score (partner→KLF14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	MYOD1 →	+0.025	+4.922	<.001	.009	3	1
BLOOD_Leukemia	FCN2 →	+0.018	+5.201	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

MYOD1 by KLF14 expression — BLOOD_Leukemia

Explore this box plot interactively →