KLC4

Across TCGA patient cohorts, KLC4 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,295 significant associations in total. GBM shows the largest number of these associations.

The most reproducible KLC4-associated proteins across cancer lineages are KLC4_S590, KLC4_S460, and PCIF1. Each is linked with KLC4 in more than 6 cancer types. Because this analysis shows association rather than direction, both KLC4-to-partner and partner-to-KLC4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KLC4 versus KLC4_S590 in PDAC, with a Pearson correlation of 0.45.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (KLC4→partner) and Y-score (partner→KLC4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	KLC4_S590 →	+0.554	+0.435	<.001	<.001	3	7
BRCA	KLC4_S460 →	+1.008	+0.809	.007	.001	2	7
GBM	PCIF1 →	+0.364	+0.322	<.001	<.001	3	6
GBM	DOK3 →	-0.499	-0.261	<.001	<.001	3	6
GBM	THEMIS2 →	-0.384	-0.247	<.001	<.001	3	6
GBM	PPP1R18 →	-0.410	-0.384	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,295 associations by consensus.

KLC4 vs KLC4_S590 — PDAC

Explore this scatter interactively →