KLC4

Across TCGA patient cohorts, KLC4 mutation is significantly associated with the RNA expression of many other genes, with 1,647 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KLC4-associated genes across cancer lineages are RN7SL483P, MIR98, and ZNHIT3. Each is linked with KLC4 in more than 1 cancer types. Because this analysis shows association rather than direction, both KLC4-to-partner and partner-to-KLC4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL483P grouped by KLC4-low versus KLC4-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KLC4→partner) and Y-score (partner→KLC4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RN7SL483P →	+0.144	+5.418	<.001	.005	3	2
LUSC	MIR98 →	+0.391	+3.554	<.001	<.001	3	2
UCEC	ZNHIT3 →	+0.389	+2.660	.003	.005	3	2
BRCA	LINC02824 →	+0.077	+4.441	<.001	.001	3	2
UCEC	GGNBP2 →	+0.333	+2.906	.007	<.001	3	2
CESC	RNA5SP259 →	+0.327	+5.103	.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,647 associations by consensus.

RN7SL483P by KLC4 expression — CESC

Explore this box plot interactively →