KLB

Across TCGA patient cohorts, KLB RNA expression is significantly associated with the protein abundance of many other proteins, with 11,059 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible KLB-associated proteins across cancer lineages are CAST_S499, RFC1_S156, and HTT_S1199. Each is linked with KLB in more than 3 cancer types. Because this analysis shows association rather than direction, both KLB-to-partner and partner-to-KLB results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KLB versus CAST_S499 in LSCC, with a Pearson correlation of -0.40.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (KLB→partner) and Y-score (partner→KLB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	CAST_S499 →	-0.759	-0.393	<.001	<.001	3	4
PDAC	RFC1_S156 →	+0.609	+0.449	<.001	<.001	3	4
LSCC	HTT_S1199 →	+0.555	+0.374	<.001	<.001	3	4
GBM	DENND4C_S1623 →	-0.891	-0.501	<.001	<.001	3	4
GBM	AHNAK_S5298 →	-0.551	-0.315	.005	.009	3	4
CCRCC	AHNAK_S5593 →	-1.040	-0.932	.004	.004	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,059 associations by consensus.

KLB vs CAST_S499 — LSCC

Explore this scatter interactively →