KIR2DP1

Across TCGA patient cohorts, KIR2DP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,016 significant associations in total. STAD shows the largest number of these associations.

The most reproducible KIR2DP1-associated GO terms across cancer lineages are Fc receptor signaling pathway, Fc-gamma receptor signaling pathway, and B cell receptor signaling pathway. Each is linked with KIR2DP1 in more than 11 cancer types. Because this analysis shows association rather than direction, both KIR2DP1-to-partner and partner-to-KIR2DP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Fc receptor signaling pathway grouped by KIR2DP1-low versus KIR2DP1-high in LAML.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KIR2DP1→partner) and Y-score (partner→KIR2DP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LAML	Fc receptor signaling pathway →	+0.042	+0.124	<.001	<.001	3	12
LAML	Fc-gamma receptor signaling pathway →	+0.059	+0.156	<.001	<.001	3	12
LAML	B cell receptor signaling pathway →	+0.046	+0.141	.001	.004	2	12
STAD	Positive regulation of lymphocyte migration →	+0.048	+0.039	<.001	<.001	3	11
STAD	Antigen receptor-mediated signaling pathway →	+0.045	+0.037	<.001	<.001	3	11
STAD	T cell receptor signaling pathway →	+0.045	+0.036	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,016 associations by consensus.

Fc receptor signaling pathway by KIR2DP1 expression — LAML

Explore this box plot interactively →