KIR2DP1

Across TCGA pan-cancer cohorts, KIR2DP1 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of KIR2DP1’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where KIR2DP1 RNA is repressed in tumor relative to normal tissue. In most cancer types KIR2DP1 is over-expressed in tumor, although a few such as LUAD and LUSC show the opposite, repressed pattern.

LUAD, LUSC, and KIRC are the cancer types where KIR2DP1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in KIR2DP1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	All	All	−0.024	.003	6	view →
LUSC	All	All	−0.048	<.001	5	view →
KIRC	All	All	+0.024	.001	5	view →
STAD	Male	II,III,IV	+0.016	.047	1	view →
COAD	All	II,III,IV	−0.009	.048	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

KIR2DP1–LUAD

Open the LUAD breakdown →