KIN

Across TCGA patient cohorts, KIN RNA expression is significantly associated with the protein abundance of many other proteins, with 8,423 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible KIN-associated proteins across cancer lineages are GDI2, UPF2, and NUDT5. Each is linked with KIN in more than 6 cancer types. Because this analysis shows association rather than direction, both KIN-to-partner and partner-to-KIN results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KIN versus GDI2 in OV, with a Pearson correlation of 0.40.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (KIN→partner) and Y-score (partner→KIN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	GDI2 →	+0.569	+0.609	.001	<.001	3	7
LSCC	UPF2 →	+0.310	+0.560	<.001	<.001	3	6
OV	NUDT5 →	+0.560	+0.348	<.001	.002	3	6
OV	CUL2 →	+0.416	+0.472	<.001	.002	2	6
GBM	MRPS34 →	-0.383	-0.341	<.001	.002	3	5
OV	LARP4B →	+0.456	+0.720	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,423 associations by consensus.

KIN vs GDI2 — OV

Explore this scatter interactively →