KIN

Across TCGA patient cohorts, KIN protein abundance is significantly associated with the RNA expression of many other genes, with 11,133 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible KIN-associated genes across cancer lineages are SUV39H2, MCM10, and SEPHS1. Each is linked with KIN in more than 6 cancer types. Because this analysis shows association rather than direction, both KIN-to-partner and partner-to-KIN results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KIN versus SUV39H2 in BRCA, with a Pearson correlation of 0.58.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIN→partner) and Y-score (partner→KIN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SUV39H2 →	+0.695	+0.369	<.001	<.001	3	7
BRCA	MCM10 →	+1.264	+0.487	<.001	<.001	3	7
BRCA	SEPHS1 →	+0.756	+0.359	<.001	<.001	3	7
BRCA	GTPBP4 →	+0.709	+0.404	<.001	<.001	3	6
HNSC	MTPAP →	+0.475	+0.143	<.001	.003	3	6
OV	TASOR2 →	+0.742	+0.376	.006	.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,133 associations by consensus.

KIN vs SUV39H2 — BRCA

Explore this scatter interactively →