KIN

Across TCGA patient cohorts, KIN protein abundance is significantly associated with the protein abundance of many other proteins, with 18,735 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible KIN-associated proteins across cancer lineages are CHERP, MCMBP, and RNF20. Each is linked with KIN in more than 7 cancer types. Because this analysis shows association rather than direction, both KIN-to-partner and partner-to-KIN results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KIN versus CHERP in BRCA, with a Pearson correlation of 0.55.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (KIN→partner) and Y-score (partner→KIN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CHERP →	+0.261	+0.388	<.001	<.001	3	8
BRCA	MCMBP →	+0.349	+0.365	<.001	<.001	3	8
LUAD	RNF20 →	+0.223	+0.286	<.001	<.001	3	8
BRCA	SAP30BP →	+0.255	+0.255	<.001	<.001	3	8
UCEC	POLD3 →	+0.370	+0.275	<.001	<.001	3	8
BRCA	RBM17 →	+0.287	+0.429	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,735 associations by consensus.

KIN vs CHERP — BRCA

Explore this scatter interactively →