KIF9

Across TCGA cell cohorts, KIF9 mutation is significantly associated with the RNA expression of many other genes, with 29 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible KIF9-associated genes across cancer lineages are OR11L1, SLC17A3, and FAM170A. Each is linked with KIF9 in more than 1 cancer types. Because this analysis shows association rather than direction, both KIF9-to-partner and partner-to-KIF9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR11L1 grouped by KIF9-low versus KIF9-high in CNS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIF9→partner) and Y-score (partner→KIF9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	OR11L1 →	+0.031	+4.981	<.001	.008	3	1
LUNG_NSCLC_LUAD	SLC17A3 →	+1.149	+4.058	<.001	<.001	3	1
LUNG_NSCLC_LUAD	FAM170A →	+0.165	+2.962	<.001	.007	3	1
LUNG_NSCLC_LUAD	AKAP14 →	+0.338	+3.491	<.001	.008	3	1
LUNG_NSCLC_LUAD	NCR1 →	+0.061	+3.043	<.001	.006	3	1
LUNG_NSCLC_LUAD	C2orf91 →	+0.205	+3.611	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 29 associations by consensus.

OR11L1 by KIF9 expression — CNS

Explore this box plot interactively →