KIF5C

Across TCGA cell cohorts, KIF5C RNA expression is significantly associated with the go_rna of many other GO terms, with 3,321 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible KIF5C-associated GO terms across cancer lineages are Anterograde dendritic transport of messenger ribonucleoprotein complex, Positive regulation of DNA repair, and Establishment of protein localization to organelle. Each is linked with KIF5C in more than 12 cancer types. Because this analysis shows association rather than direction, both KIF5C-to-partner and partner-to-KIF5C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Anterograde dendritic transport of messenger ribonucleoprotein complex grouped by KIF5C-low versus KIF5C-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KIF5C→partner) and Y-score (partner→KIF5C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Anterograde dendritic transport of messenger ribonucleoprotein complex →	-0.223	-1.521	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Positive regulation of DNA repair →	+0.083	+0.681	<.001	.005	3	13
OESOPHAGUS	Establishment of protein localization to organelle →	+0.060	+0.641	<.001	.006	3	13
SKIN	Protein-DNA complex organization →	+0.041	+1.133	<.001	.003	3	12
STOMACH	Golgi vesicle transport →	+0.054	+0.855	<.001	.008	3	12
UPPER_AERODIGESTIVE_TRACT	Regulation of DNA repair →	+0.064	+0.577	<.001	.003	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,321 associations by consensus.

Anterograde dendritic transport of messenger ribonucleoprotein complex by KIF5C expression — OVARY

Explore this box plot interactively →