KIF5B

Across TCGA patient cohorts, KIF5B protein abundance is significantly associated with the RNA expression of many other genes, with 8,242 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible KIF5B-associated genes across cancer lineages are RASGRP2, STAM, and YME1L1. Each is linked with KIF5B in more than 4 cancer types. Because this analysis shows association rather than direction, both KIF5B-to-partner and partner-to-KIF5B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KIF5B versus RASGRP2 in BRCA, with a Pearson correlation of -0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIF5B→partner) and Y-score (partner→KIF5B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RASGRP2 →	-0.641	-0.228	.001	<.001	3	5
BRCA	STAM →	+0.424	+0.198	<.001	<.001	3	5
HNSC	YME1L1 →	+0.537	+0.211	.007	<.001	3	5
LUAD	CCNY →	+0.508	+0.134	<.001	.001	3	4
GBM	COLCA1 →	-0.743	-0.238	.008	<.001	3	4
PDAC	TNFRSF13C →	-0.741	-0.157	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,242 associations by consensus.

KIF5B vs RASGRP2 — BRCA

Explore this scatter interactively →