KIF5B

Across TCGA cell cohorts, KIF5B RNA expression is significantly associated with the go_rna of many other GO terms, with 3,439 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible KIF5B-associated GO terms across cancer lineages are Regulation of metaphase/anaphase transition of cell cycle, Negative regulation of beige fat cell differentiation, and Protein localization to condensed chromosome. Each is linked with KIF5B in more than 14 cancer types. Because this analysis shows association rather than direction, both KIF5B-to-partner and partner-to-KIF5B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of metaphase/anaphase transition of cell cycle grouped by KIF5B-low versus KIF5B-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KIF5B→partner) and Y-score (partner→KIF5B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Regulation of metaphase/anaphase transition of cell cycle →	+0.098	+0.758	<.001	<.001	3	14
LIVER	Negative regulation of beige fat cell differentiation →	+0.147	+0.512	.002	.009	3	13
KIDNEY	Protein localization to condensed chromosome →	+0.162	+0.803	<.001	<.001	3	13
OVARY	Regulation of microtubule depolymerization →	+0.088	+0.854	.001	<.001	3	13
LUNG_NSCLC_LUSC	Positive regulation of organelle assembly →	+0.066	+0.814	<.001	.008	3	13
KIDNEY	Regulation of mitotic metaphase/anaphase transition →	+0.104	+0.789	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,439 associations by consensus.

Regulation of metaphase/anaphase transition of cell cycle by KIF5B expression — KIDNEY

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