KIF5B

Across TCGA cell cohorts, KIF5B mutation is significantly associated with the RNA expression of many other genes, with 336 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible KIF5B-associated genes across cancer lineages are GSG1L2, SCT, and CYP39A1. Each is linked with KIF5B in more than 1 cancer types. Because this analysis shows association rather than direction, both KIF5B-to-partner and partner-to-KIF5B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GSG1L2 grouped by KIF5B-low versus KIF5B-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIF5B→partner) and Y-score (partner→KIF5B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	GSG1L2 →	+0.034	+4.384	<.001	.006	3	2
OVARY	SCT →	+0.190	+4.029	<.001	.009	3	2
BLOOD_Leukemia	CYP39A1 →	+0.152	+3.769	<.001	.008	3	1
BLOOD_Leukemia	GPR101 →	+0.106	+3.551	<.001	.009	3	1
BLOOD_Leukemia	C16orf92 →	+0.162	+4.037	<.001	.004	3	1
BLOOD_Leukemia	TLE7 →	+0.025	+4.384	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 336 associations by consensus.

GSG1L2 by KIF5B expression — BLOOD_Leukemia

Explore this box plot interactively →