KIF2C

Across TCGA patient cohorts, KIF2C mutation is significantly associated with the RNA expression of many other genes, with 2,981 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KIF2C-associated genes across cancer lineages are LINC01202, MTCO2P21, and MTCO2P19. Each is linked with KIF2C in more than 1 cancer types. Because this analysis shows association rather than direction, both KIF2C-to-partner and partner-to-KIF2C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC01202 grouped by KIF2C-low versus KIF2C-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIF2C→partner) and Y-score (partner→KIF2C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	LINC01202 →	+0.439	+2.709	<.001	<.001	3	2
SKCM	MTCO2P21 →	+0.060	+3.096	<.001	.007	3	2
SKCM	MTCO2P19 →	+0.038	+2.902	<.001	.003	3	2
SKCM	DYNLL1P6 →	+0.211	+2.405	<.001	.006	3	2
CESC	RN7SL807P →	+0.059	+4.020	.005	.009	3	2
BRCA	RNU7-167P →	+0.759	+6.016	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,981 associations by consensus.

LINC01202 by KIF2C expression — SKCM

Explore this box plot interactively →