KIF2C

Across TCGA cell cohorts, KIF2C mutation is significantly associated with the RNA expression of many other genes, with 17 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible KIF2C-associated genes across cancer lineages are ELOA3DP, DTHD1, and FABP9. Each is linked with KIF2C in more than 1 cancer types. Because this analysis shows association rather than direction, both KIF2C-to-partner and partner-to-KIF2C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ELOA3DP grouped by KIF2C-low versus KIF2C-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIF2C→partner) and Y-score (partner→KIF2C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	ELOA3DP →	+0.030	+3.688	<.001	.002	3	2
URINARY_TRACT	DTHD1 →	+0.056	+5.087	<.001	.004	3	1
URINARY_TRACT	FABP9 →	+0.056	+5.087	<.001	.004	3	1
LUNG_NSCLC_LUAD	TAAR8 →	+0.022	+5.662	<.001	.002	3	1
LARGE_INTESTINE	SYT10 →	+0.289	+3.196	<.001	.007	3	1
BLOOD_Leukemia	OR7A10 →	+0.006	+4.569	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 17 associations by consensus.

ELOA3DP by KIF2C expression — LARGE_INTESTINE

Explore this box plot interactively →