KIF2A

Across TCGA patient cohorts, KIF2A protein abundance is significantly associated with the RNA expression of many other genes, with 17,773 significant associations in total. GBM shows the largest number of these associations.

The most reproducible KIF2A-associated genes across cancer lineages are ERCC8, CWC27, and DIMT1. Each is linked with KIF2A in more than 6 cancer types. Because this analysis shows association rather than direction, both KIF2A-to-partner and partner-to-KIF2A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KIF2A versus ERCC8 in HNSC, with a Pearson correlation of 0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIF2A→partner) and Y-score (partner→KIF2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	ERCC8 →	+0.362	+0.170	<.001	<.001	3	7
PDAC	CWC27 →	+0.530	+0.338	<.001	<.001	3	6
OV	DIMT1 →	+0.777	+0.332	<.001	<.001	3	6
PDAC	POC5 →	+0.369	+0.289	<.001	<.001	3	6
OV	PPWD1 →	+0.527	+0.256	.003	.002	2	6
COAD	TRAPPC13 →	+0.344	+0.181	<.001	.002	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,773 associations by consensus.

KIF2A vs ERCC8 — HNSC

Explore this scatter interactively →