KIF2A

Across TCGA cell cohorts, KIF2A RNA expression is significantly associated with the go_rna of many other GO terms, with 4,543 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible KIF2A-associated GO terms across cancer lineages are Centrosome cycle, Centrosome duplication, and Microtubule organizing center organization. Each is linked with KIF2A in more than 16 cancer types. Because this analysis shows association rather than direction, both KIF2A-to-partner and partner-to-KIF2A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Centrosome cycle grouped by KIF2A-low versus KIF2A-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KIF2A→partner) and Y-score (partner→KIF2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Centrosome cycle →	+0.101	+1.100	<.001	<.001	3	17
SOFT_TISSUE	Centrosome duplication →	+0.107	+1.053	<.001	<.001	3	17
SOFT_TISSUE	Microtubule organizing center organization →	+0.090	+1.142	<.001	<.001	3	16
BREAST	Regulation of sister chromatid segregation →	+0.118	+1.030	<.001	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	Protein localization to chromosome →	+0.105	+1.241	<.001	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	Negative regulation of cell cycle process →	+0.082	+1.353	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,543 associations by consensus.

Centrosome cycle by KIF2A expression — SOFT_TISSUE

Explore this box plot interactively →