KIF26B

Across TCGA pan-cancer cohorts, KIF26B mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated KIF26B data layer compared with 23 for mass-spec protein and 14 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher KIF26B mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated KIF26B expression acts as an unfavorable survival marker, although some lineages such as UCEC and HNSC show a favorable association.

UCEC, HNSC, and CCRCC are the cancer types where KIF26B mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Tertile	All	1.000	0.809	.013	18	view →
HNSC	OS	Median	II,III,IV	0.927	0.769	.012	9	view →
CCRCC	DFS	Median	III,IV	0.145	0.774	.016	8	view →
LUAD	DFS	Quartile	All	0.509	0.873	.037	3	view →
GBM	OS	Tertile	All	0.908	0.622	.036	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

KIF26B–UCEC (OS)

Open the UCEC breakdown →