KIF26B-AS1

Across TCGA pan-cancer cohorts, KIF26B-AS1 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated KIF26B-AS1 data layer.

The strongest signal is observed in mesothelioma (MESO), where higher KIF26B-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated KIF26B-AS1 expression acts as an unfavorable survival marker, although some lineages such as LUAD and UCEC show a favorable association.

MESO, LUAD, and LIHC are the cancer types where KIF26B-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	OS	Median	All	0.389	0.633	<.001	78	view →
LUAD	DFS	Tertile	All	0.851	0.731	<.001	70	view →
LIHC	OS	Tertile	All	0.535	0.719	.001	66	view →
OV	OS	Median	IV	0.273	0.479	.006	48	view →
UCEC	DFS	Quartile	II,III,IV	0.901	0.749	.010	44	view →
HNSC	OS	Median	IV	0.149	0.397	.005	42	view →
LGG	DFS	Tertile	All	0.747	0.865	<.001	36	view →
LAML	DFS	Median	All	0.506	0.262	.001	34	view →
KICH	OS	Tertile	All	0.773	0.952	.014	27	view →
LUSC	DFS	Tertile	II,III,IV	0.920	0.586	.005	24	view →
READ	DFS	Quartile	All	0.332	0.770	.006	17	view →
THCA	OS	Quartile	II,III,IV	0.789	0.954	.008	13	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

KIF26B-AS1–MESO (OS)

Open the MESO breakdown →