KIF26B-AS1

Across TCGA pan-cancer cohorts, KIF26B-AS1 RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of KIF26B-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where KIF26B-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types KIF26B-AS1 is over-expressed in tumor, although a few such as THCA and LUSC show the opposite, repressed pattern.

THCA, LUSC, and STAD are the cancer types where KIF26B-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in KIF26B-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	Female	II,III,IV	−0.385	<.001	8	view →
LUSC	All	II,III,IV	−0.697	<.001	7	view →
STAD	Male	All	+0.550	<.001	6	view →
BRCA	All	IV	+0.185	<.001	6	view →
KIRC	All	II,III,IV	−0.104	<.001	6	view →
KIRP	All	II,III,IV	+0.204	.009	4	view →
CHOL	All	II,III,IV	+1.509	.006	3	view →
KICH	All	All	−0.164	.002	3	view →
HNSC	Male	All	+0.062	.004	3	view →
ESCA	All	II,III,IV	+0.989	.035	2	view →
COAD	All	All	+0.055	.031	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

KIF26B-AS1–THCA

Open the THCA breakdown →