KIF25-AS1

Across TCGA pan-cancer cohorts, KIF25-AS1 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of KIF25-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where KIF25-AS1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types KIF25-AS1 is over-expressed in tumor, although a few such as KICH and BRCA show the opposite, repressed pattern.

LUAD, KICH, and BRCA are the cancer types where KIF25-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in KIF25-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	All	All	+0.484	<.001	8	view →
KICH	All	All	−0.708	.004	4	view →
BRCA	All	III,IV	−0.136	.005	2	view →
STAD	All	All	+0.322	.043	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

KIF25-AS1–LUAD

Open the LUAD breakdown →