KIF23

Across TCGA patient cohorts, KIF23 RNA expression is significantly associated with the protein abundance of many other proteins, with 25,401 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible KIF23-associated proteins across cancer lineages are NCL_S67, NUF2_S247, and PAICS_S27. Each is linked with KIF23 in more than 9 cancer types. Because this analysis shows association rather than direction, both KIF23-to-partner and partner-to-KIF23 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KIF23 versus NCL_S67 in LUAD, with a Pearson correlation of 0.70.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (KIF23→partner) and Y-score (partner→KIF23) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	NCL_S67 →	+1.045	+1.178	<.001	<.001	3	10
LUAD	NUF2_S247 →	+1.318	+1.223	<.001	<.001	3	10
LUAD	PAICS_S27 →	+1.337	+1.183	<.001	<.001	3	10
LUAD	TOP2A_S1247 →	+1.579	+1.265	<.001	<.001	3	10
LUAD	TRIP13 →	+0.928	+1.172	<.001	<.001	3	10
OV	POLD1 →	+0.402	+1.096	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 25,401 associations by consensus.

KIF23 vs NCL_S67 — LUAD

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