KIF22

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, KIF22 RNA expression is significantly associated with the protein abundance of many other proteins, with 20,300 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible KIF22-associated proteins across cancer lineages are RFC4, MCM3, and PRIM2. Each is linked with KIF22 in more than 9 cancer types. Because this analysis shows association rather than direction, both KIF22-to-partner and partner-to-KIF22 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KIF22 versus RFC4 in LSCC, with a Pearson correlation of 0.64.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (KIF22→partner) and Y-score (partner→KIF22) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCRFC4 →+0.537+0.784<.001<.001310
LSCCMCM3 →+0.740+0.782<.001<.001310
OVPRIM2 →+0.521+0.808<.001<.00139
LSCCVRK1 →+0.562+0.794<.001<.00139
BRCAATAD2 →+0.619+0.547<.001<.00139
LUADATAD2_S342 →+1.319+0.572<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 20,300 associations by consensus.

KIF22 vs RFC4 — LSCC

Per-sample scatter of KIF22 vs RFC4 in LSCC (Pearson r = 0.64).

Explore this scatter interactively →

Exploration