KIF21B

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, KIF21B protein abundance is significantly associated with the RNA expression of many other genes, with 8,336 significant associations in total. GBM shows the largest number of these associations.

The most reproducible KIF21B-associated genes across cancer lineages are CXCL1, CCDC178, and PIPSL. Each is linked with KIF21B in more than 2 cancer types. Because this analysis shows association rather than direction, both KIF21B-to-partner and partner-to-KIF21B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KIF21B versus CXCL1 in OV, with a Pearson correlation of 0.44.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIF21B→partner) and Y-score (partner→KIF21B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVCXCL1 →+1.462+0.826.002<.00132
OVCCDC178 →+0.429+0.825.007.00132
OVPIPSL →+1.576+1.004<.001.00332
OVGAPDHP44 →+1.220+0.872.001.00732
OVANXA2P1 →+1.652+0.796.003.00932
OVKRT8P41 →+0.431+0.777.003.00532
Each partner links to its Q-omics profile. Showing the 6 strongest of 8,336 associations by consensus.

KIF21B vs CXCL1 — OV

Per-sample scatter of KIF21B vs CXCL1 in OV (Pearson r = 0.44).

Explore this scatter interactively →

Exploration