KIF21B

Across TCGA cell cohorts, KIF21B RNA expression is significantly associated with the go_rna of many other GO terms, with 3,229 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible KIF21B-associated GO terms across cancer lineages are Regulation of myoblast fusion, Transsulfuration, and Response to endoplasmic reticulum stress. Each is linked with KIF21B in more than 10 cancer types. Because this analysis shows association rather than direction, both KIF21B-to-partner and partner-to-KIF21B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of myoblast fusion grouped by KIF21B-low versus KIF21B-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KIF21B→partner) and Y-score (partner→KIF21B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Regulation of myoblast fusion →	+0.088	+1.123	.008	.007	2	11
LUNG_NSCLC_LUAD	Transsulfuration →	+0.136	+1.051	<.001	<.001	3	8
BLOOD_Myeloma	Response to endoplasmic reticulum stress →	+0.069	+1.104	.001	.002	3	7
SOFT_TISSUE	Regulation of mRNA stability →	+0.061	+1.011	<.001	<.001	3	7
BLOOD_Myeloma	Hydrogen sulfide metabolic process →	+0.189	+1.197	<.001	<.001	3	7
LUNG_SCLC	Negative regulation of myoblast fusion →	+0.102	+1.650	<.001	.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,229 associations by consensus.

Regulation of myoblast fusion by KIF21B expression — PANCREAS

Explore this box plot interactively →