KIF20A

Across TCGA cell cohorts, KIF20A RNA expression is significantly associated with the go_rna of many other GO terms, with 4,324 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible KIF20A-associated GO terms across cancer lineages are Positive regulation of cell cycle process, Nuclear chromosome segregation, and Mitotic spindle elongation. Each is linked with KIF20A in more than 19 cancer types. Because this analysis shows association rather than direction, both KIF20A-to-partner and partner-to-KIF20A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of cell cycle process grouped by KIF20A-low versus KIF20A-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KIF20A→partner) and Y-score (partner→KIF20A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Positive regulation of cell cycle process →	+0.094	+1.035	<.001	<.001	3	20
OESOPHAGUS	Nuclear chromosome segregation →	+0.116	+1.440	<.001	<.001	3	20
LUNG_NSCLC_LUSC	Mitotic spindle elongation →	+0.328	+2.189	<.001	<.001	3	20
BONE	Meiotic chromosome segregation →	+0.160	+1.329	.005	.004	3	20
SOFT_TISSUE	Positive regulation of cell cycle →	+0.066	+1.059	<.001	<.001	3	20
BLOOD_Myeloma	Spindle elongation →	+0.268	+1.387	<.001	.002	3	20

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,324 associations by consensus.

Positive regulation of cell cycle process by KIF20A expression — PANCREAS

Explore this box plot interactively →