KIF20A

Across TCGA cell cohorts, KIF20A mutation is significantly associated with the RNA expression of many other genes, with 23 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible KIF20A-associated genes across cancer lineages are GHRH, PLA2G2D, and C16orf92. Each is linked with KIF20A in more than 1 cancer types. Because this analysis shows association rather than direction, both KIF20A-to-partner and partner-to-KIF20A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GHRH grouped by KIF20A-low versus KIF20A-high in OESOPHAGUS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIF20A→partner) and Y-score (partner→KIF20A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	GHRH →	+0.060	+4.906	<.001	.006	3	1
LUNG_NSCLC_LUAD	PLA2G2D →	+0.132	+3.760	<.001	.008	3	1
LUNG_NSCLC_LUAD	C16orf92 →	+0.048	+3.947	<.001	.004	3	1
LUNG_NSCLC_LUAD	PATE3 →	+0.047	+3.745	.002	.008	3	1
LUNG_NSCLC_LUAD	CT45A9 →	+1.121	+3.544	<.001	.009	3	1
LARGE_INTESTINE	ASPN →	+0.032	+3.648	.008	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 23 associations by consensus.

GHRH by KIF20A expression — OESOPHAGUS

Explore this box plot interactively →