KIF13A

Across TCGA pan-cancer cohorts, KIF13A mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated KIF13A data layer compared with 24 for mass-spec protein and 7 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher KIF13A mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated KIF13A expression acts as an unfavorable survival marker, although some lineages such as HNSC and LUAD show a favorable association.

HNSC, LUAD, and GBM are the cancer types where KIF13A mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Tertile	All	0.866	0.533	<.001	77	view →
LUAD	OS	Median	All	1.000	0.773	.006	7	view →
GBM	OS	Median	All	0.763	0.944	.002	5	view →
PDAC	OS	Median	III,IV	0.647	0.265	.020	4	view →
CCRCC	DFS	Median	II,III,IV	0.830	0.605	.042	3	view →
LSCC	DFS	Tertile	All	0.999	0.844	.019	2	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

KIF13A–HNSC (OS)

Open the HNSC breakdown →