KIF13A

Across TCGA pan-cancer cohorts, KIF13A RNA differs between tumor and matched normal tissue in 13 of 18 cancer types tested, making tumor–normal expression one of KIF13A’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where KIF13A RNA is more highly expressed in tumor relative to normal tissue. In most cancer types KIF13A is over-expressed in tumor, although a few such as THCA and UCEC show the opposite, repressed pattern.

HNSC, LIHC, and THCA are the cancer types where KIF13A tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in KIF13A RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	Female	III,IV	+1.261	<.001	12	view →
LIHC	Female	II,III,IV	+0.934	<.001	9	view →
THCA	All	All	−0.430	.001	7	view →
UCEC	All	All	−1.224	<.001	6	view →
BRCA	All	III,IV	−0.645	<.001	6	view →
BLCA	All	IV	−1.151	.012	5	view →
KICH	Female	All	−0.996	<.001	4	view →
LUAD	All	All	−0.371	<.001	4	view →
CHOL	Male	All	+1.620	<.001	3	view →
READ	All	All	−1.022	<.001	3	view →
STAD	Male	II,III,IV	+0.794	.045	1	view →
KIRP	Male	All	−0.316	.040	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 13 lineages.

KIF13A–HNSC

Open the HNSC breakdown →