KIF13A

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, KIF13A mutation is significantly associated with the RNA expression of many other genes, with 3,695 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KIF13A-associated genes across cancer lineages are RNU6-1054P, ENO2, and RNU6-203P. Each is linked with KIF13A in more than 3 cancer types. Because this analysis shows association rather than direction, both KIF13A-to-partner and partner-to-KIF13A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-1054P grouped by KIF13A-low versus KIF13A-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIF13A→partner) and Y-score (partner→KIF13A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
HNSCRNU6-1054P →+0.276+3.017.007.00434
SKCMENO2 →+0.911+1.671.002.00334
CESCRNU6-203P →+0.219+4.020<.001.00933
PRADTRIM51EP →+0.236+4.424<.001<.00133
UCECADAM33 →-0.734-3.195<.001<.00133
UCECGBP4 →+0.597+1.785.001.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,695 associations by consensus.

RNU6-1054P by KIF13A expression — HNSC

Box plot of RNU6-1054P in KIF13A-low vs KIF13A-high samples in HNSC.

Explore this box plot interactively →

Exploration