KIF13A

Across TCGA patient cohorts, KIF13A mutation is significantly associated with the total protein of many other genes, with 60 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KIF13A-associated genes across cancer lineages are TFRC, PAI-1, and Caspase-7-cleavedD198. Each is linked with KIF13A in more than 3 cancer types. Because this analysis shows association rather than direction, both KIF13A-to-partner and partner-to-KIF13A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TFRC grouped by KIF13A-low versus KIF13A-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIF13A→partner) and Y-score (partner→KIF13A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	TFRC →	+0.484	+2.459	.024	.020	3	4
COAD	PAI-1 →	+0.931	+3.017	<.001	.017	3	4
UCEC	Caspase-7-cleavedD198 →	+0.514	+2.090	.003	<.001	3	3
STAD	4E-BP1 →	+0.307	+3.000	.047	.036	2	4
SKCM	Rb_pS807_S811 →	+0.550	+1.874	.001	.049	3	3
UCEC	PCNA →	+0.153	+1.241	.015	.015	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 60 associations by consensus.

TFRC by KIF13A expression — BLCA

Explore this box plot interactively →