KIF13A

Across TCGA cell cohorts, KIF13A RNA expression is significantly associated with the go_rna of many other GO terms, with 5,093 significant associations in total. BONE shows the largest number of these associations.

The most reproducible KIF13A-associated GO terms across cancer lineages are Positive regulation of cellular response to transforming growth factor beta stimulus, Positive regulation of transforming growth factor beta receptor signaling pathway, and Regulation of fibroblast proliferation. Each is linked with KIF13A in more than 11 cancer types. Because this analysis shows association rather than direction, both KIF13A-to-partner and partner-to-KIF13A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of cellular response to transforming growth factor beta stimulus grouped by KIF13A-low versus KIF13A-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KIF13A→partner) and Y-score (partner→KIF13A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Positive regulation of cellular response to transforming growth factor beta stimulus →	+0.137	+1.316	<.001	<.001	3	12
BONE	Positive regulation of transforming growth factor beta receptor signaling pathway →	+0.137	+1.316	<.001	<.001	3	12
SOFT_TISSUE	Regulation of fibroblast proliferation →	+0.098	+0.804	<.001	<.001	3	11
BONE	Regulation of focal adhesion assembly →	+0.148	+1.245	<.001	<.001	3	11
BONE	Regulation of cell-substrate junction assembly →	+0.148	+1.245	<.001	<.001	3	11
STOMACH	Vesicle cytoskeletal trafficking →	+0.106	+1.571	<.001	.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,093 associations by consensus.

Positive regulation of cellular response to transforming growth factor beta stimulus by KIF13A expression — BONE

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