KIDINS220

Across TCGA pan-cancer cohorts, KIDINS220 Mutation is linked to patient survival in 5 of 34 cancer types, making it a survival-associated KIDINS220 data layer compared with 24 for mass-spec protein and 5 for mass-spec protein.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher KIDINS220 Mutation is associated with better disease-free survival. In most high-consensus cancer types, elevated KIDINS220 expression acts as an unfavorable survival marker, although some lineages such as UCEC and SKCM show a favorable association.

UCEC, LUSC, and TGCT are the cancer types where KIDINS220 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Median	II,III,IV	0.941	0.299	.003	32	view →
LUSC	OS	Median	III,IV	0.068	0.691	<.001	12	view →
TGCT	DFS	Median	All	0.067	0.802	.001	6	view →
LUAD	OS	Median	II,III,IV	0.307	0.748	.046	3	view →
SKCM	DFS	Median	All	0.805	0.609	.031	2	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

KIDINS220–UCEC (DFS)

Open the UCEC breakdown →