KIDINS220

Across TCGA pan-cancer cohorts, KIDINS220 RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of KIDINS220’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where KIDINS220 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types KIDINS220 is over-expressed in tumor, although a few such as KICH and BRCA show the opposite, repressed pattern.

HNSC, KICH, and CHOL are the cancer types where KIDINS220 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in KIDINS220 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	All	III,IV	+0.875	<.001	11	view →
KICH	Female	All	−0.987	<.001	7	view →
CHOL	All	All	+1.483	<.001	5	view →
LIHC	Female	All	+0.723	<.001	5	view →
BRCA	Female	All	−0.232	.001	4	view →
LUAD	All	All	−0.305	.009	3	view →
READ	All	All	−0.637	.005	2	view →
KIRP	Male	All	−0.567	.004	2	view →
UCEC	All	All	−0.548	.023	2	view →
COAD	Female	All	−0.351	.042	1	view →
KIRC	Male	II,III,IV	−0.306	.029	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

KIDINS220–HNSC

Open the HNSC breakdown →