KIDINS220

Across TCGA cell cohorts, KIDINS220 mutation is significantly associated with the RNA expression of many other genes, with 516 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible KIDINS220-associated genes across cancer lineages are CSNKA2IP, C10orf53, and FABP12. Each is linked with KIDINS220 in more than 1 cancer types. Because this analysis shows association rather than direction, both KIDINS220-to-partner and partner-to-KIDINS220 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CSNKA2IP grouped by KIDINS220-low versus KIDINS220-high in LUNG_SCLC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIDINS220→partner) and Y-score (partner→KIDINS220) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	CSNKA2IP →	+0.083	+3.070	<.001	.009	3	2
LARGE_INTESTINE	C10orf53 →	+0.007	+2.310	.005	.005	3	2
BLOOD_Leukemia	FABP12 →	+0.050	+3.464	<.001	.003	3	2
BLOOD_Myeloma	OR2A5 →	+0.040	+4.807	<.001	.006	3	1
BLOOD_Myeloma	H3C11 →	+0.416	+4.807	<.001	.006	3	1
LUNG_NSCLC_LUAD	SEL1L2 →	+0.020	+3.362	.005	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 516 associations by consensus.

CSNKA2IP by KIDINS220 expression — LUNG_SCLC

Explore this box plot interactively →