KIAA2026

Across TCGA patient cohorts, KIAA2026 mutation is significantly associated with the total protein of many other genes, with 34 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KIAA2026-associated genes across cancer lineages are 4E-BP1, ASNS, and Claudin-7. Each is linked with KIAA2026 in more than 3 cancer types. Because this analysis shows association rather than direction, both KIAA2026-to-partner and partner-to-KIAA2026 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, 4E-BP1 grouped by KIAA2026-low versus KIAA2026-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIAA2026→partner) and Y-score (partner→KIAA2026) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	4E-BP1 →	+0.203	+2.115	.007	.016	3	4
UCEC	ASNS →	+0.301	+0.947	.003	.047	3	3
BLCA	Claudin-7 →	+0.554	+1.999	.035	.031	3	2
COAD	Caspase-7-cleavedD198 →	+0.886	+3.016	.013	.018	3	2
UCEC	Ku80 →	+0.173	+0.960	.009	.033	3	2
UCEC	Notch1 →	+0.129	+2.009	.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 34 associations by consensus.

4E-BP1 by KIAA2026 expression — UCEC

Explore this box plot interactively →