KIAA2026

Across TCGA pan-cancer cohorts, KIAA2026 RNA differs between tumor and matched normal tissue in 7 of 18 cancer types tested, making tumor–normal expression one of KIAA2026’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where KIAA2026 RNA is repressed in tumor relative to normal tissue. In most cancer types KIAA2026 is over-expressed in tumor, although a few such as THCA and KIRC show the opposite, repressed pattern.

THCA, CHOL, and LIHC are the cancer types where KIAA2026 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in KIAA2026 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	All	All	−0.439	<.001	8	view →
CHOL	Male	All	+1.824	<.001	4	view →
LIHC	All	All	+0.356	.002	4	view →
KIRC	All	II,III,IV	−0.308	.007	4	view →
HNSC	All	III,IV	+0.518	.028	3	view →
UCEC	All	All	−0.628	<.001	2	view →
LUSC	Male	All	−0.271	.017	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 7 strongest of 7 lineages.

KIAA2026–THCA

Open the THCA breakdown →