KIAA2026

Across TCGA cell cohorts, KIAA2026 mutation is significantly associated with the RNA expression of many other genes, with 713 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible KIAA2026-associated genes across cancer lineages are GOLIM4, KXD1, and ADSL. Each is linked with KIAA2026 in more than 3 cancer types. Because this analysis shows association rather than direction, both KIAA2026-to-partner and partner-to-KIAA2026 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GOLIM4 grouped by KIAA2026-low versus KIAA2026-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIAA2026→partner) and Y-score (partner→KIAA2026) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	GOLIM4 →	+1.015	+3.321	.001	.004	3	3
LARGE_INTESTINE	KXD1 →	+0.299	+1.714	.006	.006	2	4
LARGE_INTESTINE	ADSL →	+0.469	+2.545	.002	<.001	3	3
UPPER_AERODIGESTIVE_TRACT	OR52B2 →	+0.026	+3.039	<.001	.003	3	3
BONE	SIGLEC5 →	+0.023	+5.169	<.001	.004	3	2
BONE	CYLC1 →	+0.013	+5.169	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 713 associations by consensus.

GOLIM4 by KIAA2026 expression — BLOOD_Lymphoma

Explore this box plot interactively →