KIAA2013

Across TCGA cell cohorts, KIAA2013 mutation is significantly associated with the RNA expression of many other genes, with 20 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible KIAA2013-associated genes across cancer lineages are TRPC5, RBMY1A1, and KRTAP17-1. Each is linked with KIAA2013 in more than 1 cancer types. Because this analysis shows association rather than direction, both KIAA2013-to-partner and partner-to-KIAA2013 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TRPC5 grouped by KIAA2013-low versus KIAA2013-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIAA2013→partner) and Y-score (partner→KIAA2013) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	TRPC5 →	+0.006	+3.882	.006	.003	3	2
BREAST	RBMY1A1 →	+0.006	+5.781	<.001	.001	3	1
SKIN	KRTAP17-1 →	+0.025	+4.977	<.001	.007	3	1
LUNG_NSCLC_LUAD	OR4F5 →	+0.007	+3.887	<.001	.002	3	1
LUNG_NSCLC_LUAD	SKOR2 →	+0.012	+3.362	<.001	.007	3	1
LARGE_INTESTINE	MAGEB4 →	+0.012	+3.678	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 20 associations by consensus.

TRPC5 by KIAA2013 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →