KIAA2013

Across TCGA pan-cancer cohorts, KIAA2013 RNA differs between tumor and matched normal tissue in 13 of 18 cancer types tested, making tumor–normal expression one of KIAA2013’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where KIAA2013 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types KIAA2013 is over-expressed in tumor, although a few such as KICH and KIRP show the opposite, repressed pattern.

HNSC, KICH, and BLCA are the cancer types where KIAA2013 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in KIAA2013 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	Male	III,IV	+0.791	<.001	12	view →
KICH	All	III,IV	−1.282	<.001	10	view →
BLCA	All	All	+0.512	<.001	10	view →
THCA	Female	II,III,IV	+0.770	<.001	9	view →
LUSC	Female	All	+0.649	<.001	8	view →
KIRC	Female	All	+0.414	<.001	8	view →
STAD	Male	II,III,IV	+1.122	<.001	6	view →
UCEC	All	All	+0.550	<.001	6	view →
LUAD	All	III,IV	+0.382	.001	6	view →
BRCA	All	All	+0.210	.001	6	view →
PAAD	Female	All	+0.360	.021	4	view →
LIHC	All	All	+0.294	.002	3	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 13 lineages.

KIAA2013–HNSC

Open the HNSC breakdown →